Fat inhibition of gastric acid secretion in duodenal ulcer patients before and after proximal gastric vagotomy.
نویسندگان
چکیده
In seven duodenal ulcer patients the effect of intraduodenal infusion of 20 ml oleic acid on submaximal gastric acid secretion stimulation by a continuous pentagastrin infusion was evaluated before and after proximal gastric vagotomy. In the control tests 20 ml of saline was given. Before vagotomy, oleic acid evoked a significant inhibition of gastric acid secretion of 25% compared with the controls. This inhibition was abolished after proximal gastric vagotomy. The difference in inhibition before and after vagotomy was significant (P=0.01). It is concluded that the vagus nerve in man plays a decisive role in duodenal fat inhibition of gastric acid secretion.
منابع مشابه
Fat inhibition of gastric acid secretion in duodenal ulcer
In seven duodenal ulcer patients the effect of intraduodenal infusion of 20 ml oleic. acid on submaximal gastric acid secretion stimulated by a continuous pentagastrin infusion was evaluated before and after proximal gastric vagotomy. In the control tests 20 ml of saline was given. Before vagotomy, oleic acid evoked a significant inhibition of gastric acid secretion of 25 % compared with the co...
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عنوان ژورنال:
- Gut
دوره 21 12 شماره
صفحات -
تاریخ انتشار 1980